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17 Case faculty members receive Presidential Research Initiative grants to pursue interdisciplinary research

Grants fund eight projects, seven of which involve School of Medicine faculty

 

CLEVELAND (June 27, 2005) – Seventeen Case Western Reserve University researchers representing four of the university’s schools and colleges have been awarded $960,000 to fund eight research projects under a program designed to promote interdisciplinary research. Seven of the eight projects involve School of Medicine faculty members.

 

The Presidential Research Initiative (PRI) grant program recently made grants of $80,000 to each of the studies. The grants were matched by grants of $40,000 from the four schools in which the faculty members work, for a total of $120,000 per study.

 

“We were extremely happy with the diversity and quality of the proposals the researchers submitted for funding,” said Eric Cottington, associate vice president for research. “The program is designed to encourage researchers from different disciplines to collaborate, and it is attaining that goal.”

 

Researchers and the proposals for which they received funding:

 

·          Matthias Buck, Ph.D., assistant professor of biophysics and physiology at the School of Medicine, and Jie Shan, Ph.D., an assistant professor of physics in the College of Arts and Sciences, for an experimental project using terahertz spectroscopy to probe proteins in varying states. Results of the study will help determine whether terahertz spectroscopy can be used to detect cancer and other diseased cells in human tissue.

·          Kevin Bunting, Ph.D., associate professor of medicine at the medical school, and Xin Yu, Sc.D., associate professor of biomedical engineering (a joint department of Case’s medical and engineering schools), to develop stem cell therapy and delivery methods for treating heart damage in mice, and to develop magnetic resonance imaging (MRI) techniques for evaluating the efficiency of stem cell therapy in small animals.

·          Randall Cebul, M.D., professor of medicine and epidemiology and biostatistics at the School of Medicine; Mark Votruba, Ph.D., assistant professor of economics in the Weatherhead School of Management; and James Rebitzer, Ph.D., chair and professor of economics at the management school, to investigate the rate of turnover in membership of insurance plans.

·          Thomas Egelhoff, Ph.D., associate professor of physiology and biophysics in the medical school, and Harihara Baskaran, Ph.D., assistant professor of chemical engineering and assistant professor of biomedical engineering, to study how human breast cancer cells migrate from the primary tumor to new locations in the body (metastasis). The studies are designed to provide a foundation for identifying new targets for anti-cancer chemotherapy.

·          Agata Exner, Ph.D., assistant professor of radiology at the School of Medicine and assistant professor of biomedical engineering, and Cheri Deng, Ph.D., assistant professor of biomedical engineering, for developing an ultrasound-mediated method for targeted delivery of drugs to cells for cancer treatment and other applications.

·          Melissa Knothe Tate, Ph.D., associate professor in the departments of biomedical engineering and mechanical and aerospace engineering, and Radhika Atit, Ph.D., assistant professor of biology in the College of Arts and Sciences, for an examination of how mechanical stress is processed in a cell to direct the fate of the cell. The knowledge will help prevent and treat skeletal defects during an embryo’s development and to accelerate fracture repair after birth.

·          Michiko Watanabe, Ph.D., associate professor of pediatrics at the medical school, and Andrew Rollins, Ph.D., assistant professor of medicine in the School of Medicine and assistant professor of biomedical engineering, for a project to develop techniques for imaging hearts in the embryo stage, with the ultimate goal of treating congenital heart defects in the embryonic stage.

·          James Van Orman, Ph.D., assistant professor of geological sciences in the College of Arts and Sciences, and Daniel Lacks, Ph.D., professor of chemical engineering in the School of Engineering, for investigating the influence of volatile components such as water and carbon dioxide on the physical properties of magmas.

 

The PRI funds are distributed through the office of the president and provost using a research challenge grant from the Ohio Board of Regents, and from proceeds the university receives from commercializing intellectual property.

 

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