| DESCRIPTION : The host defense against invading microbial pathogens undergoes unique development during early childhood leading to a mature immune system as a young adult. The area of concentration of developmental host defense is designed to explore in detail the interactions of the developing host defense system such as T & B lymphocytes, antibodies, complement and macrophages with various bacteria and viruses that are particularly problematic for children whose immune systems are not yet mature (and adults with defined immunodeficiencies). The course of study will involve preclinical course work followed by clinical electives that will involve care and longitudinal follow-up of children with infections and/or immunologic problems.
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